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Prospects and Challenges in the Development of Universal Influenza Vaccines.

ABSTRACT: Current influenza vaccines offer suboptimal protection and depend on annual reformulation and yearly administration. Vaccine technology has rapidly advanced during the last decade, facilitating development of next-generation influenza vaccines that can target a broader range of influenza viruses. The development and licensure of a universal influenza vaccine could provide a game changing option for the control of influenza by protecting against all influenza A and B viruses. Here we review important findings and considerations regarding the development of universal influenza vaccines and what we can learn from this moving forward with a SARS-CoV-2 vaccine design.

SUBMITTER: Madsen A

PROVIDER: S-EPMC7563311 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature

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Prospects and Challenges in the Development of Universal Influenza Vaccines.

Madsen Anders A Cox Rebecca Jane RJ

Vaccines 20200706 3

Current influenza vaccines offer suboptimal protection and depend on annual reformulation and yearly administration. Vaccine technology has rapidly advanced during the last decade, facilitating development of next-generation influenza vaccines that can target a broader range of influenza viruses. The development and licensure of a universal influenza vaccine could provide a game changing option for the control of influenza by protecting against all influenza A and B viruses. Here we review impor ...[more]

PMID: 32640619

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