Dataset Information

Galectins in Intra- and Extracellular Vesicles.

ABSTRACT: Carbohydrate-binding galectins are expressed in various tissues of multicellular organisms. They are involved in autophagy, cell migration, immune response, inflammation, intracellular transport, and signaling. In recent years, novel roles of galectin-interaction with membrane components have been characterized, which lead to the formation of vesicles with diverse functions. These vesicles are part of intracellular transport pathways, belong to the cellular degradation machinery, or can be released for cell-to-cell communication. Several characteristics of galectins in the lumen or at the membrane of newly formed vesicular structures are discussed in this review and illustrate the need to fully elucidate their contributions at the molecular and structural level.

SUBMITTER: Banfer S

PROVIDER: S-EPMC7563435 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature

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Galectins in Intra- and Extracellular Vesicles.

Bänfer Sebastian S Jacob Ralf R

Biomolecules 20200824 9

Carbohydrate-binding galectins are expressed in various tissues of multicellular organisms. They are involved in autophagy, cell migration, immune response, inflammation, intracellular transport, and signaling. In recent years, novel roles of galectin-interaction with membrane components have been characterized, which lead to the formation of vesicles with diverse functions. These vesicles are part of intracellular transport pathways, belong to the cellular degradation machinery, or can be relea ...[more]

PMID: 32847140

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Dataset Information

Galectins in Intra- and Extracellular Vesicles.

Publications

Galectins in Intra- and Extracellular Vesicles.

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