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In vitro screening of peptidase inhibitory activity in some plants of North India.


ABSTRACT: In the present study, trypsin and chymotrypsin inhibitory activity of some plants of different families was evaluated. A total of 55 plants were screened, out of which six showed the maximum trypsin inhibitory activity namely Acacia concinna, Caesalpinia bonducella, Lathyrus sativus, Mucuna pruriens, Psoralea corylifolia and Sapindus mukorossi. Results suggested that the plants showing trypsin inhibitory activity (TIA) also have chymotrypsin inhibitory activity (CIA). Both trypsin and chymotrypsin inhibitory activities were high in seeds compared to leaves followed by flowers. It was also observed that TIA was maximally present in Sapindaceae family whereas CIA was maximum in fabaceae family followed by others.

SUBMITTER: Samiksha 

PROVIDER: S-EPMC7566102 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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In vitro screening of peptidase inhibitory activity in some plants of North India.

Samiksha   Sohal Satwinder Kaur SK  

Heliyon 20201013 10


In the present study, trypsin and chymotrypsin inhibitory activity of some plants of different families was evaluated. A total of 55 plants were screened, out of which six showed the maximum trypsin inhibitory activity namely <i>Acacia concinna, Caesalpinia bonducella, Lathyrus sativus, Mucuna pruriens, Psoralea corylifolia</i> and <i>Sapindus mukorossi</i>. Results suggested that the plants showing trypsin inhibitory activity (TIA) also have chymotrypsin inhibitory activity (CIA). Both trypsin  ...[more]

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