Cytologic studies of in vivo fallopian tube specimens in patients undergoing salpingo-oophorectomy.

ABSTRACT:

Objectives

Recent research shows that most high grade ovarian cancer (OC) originates from the fallopian tube (FT). Cytologic evaluation of FT cells may enable early detection of OC.

Material and methods

This was a prospective study with patients enrolled from 3 centers (October 2016- August 2017). Forty-two women undergoing salpingo-oophorectomy for a pelvic mass suspicious for malignancy or undergoing risk-reducing surgery for BRCA mutations were included in the study. At the time of scheduled surgery, a novel catheter was used to collect FT cells through hysteroscopy. A pathologist blinded to surgical or pathologic findings evaluated FT cytology, and results were compared to pathology.

Results

Of the 61 samples collected, 72% (44/61) met the adequacy criteria

SUBMITTER: Pramanik S 

PROVIDER: S-EPMC7568227 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature