Antibiotic affects the gut microbiota composition and expression of genes related to lipid metabolism and myofiber types in skeletal muscle of piglets.
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ABSTRACT:
SUBMITTER: Yan H
PROVIDER: S-EPMC7568366 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
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Antibiotic affects the gut microbiota composition and expression of genes related to lipid metabolism and myofiber types in skeletal muscle of piglets.
Yan Honglin H Yu Bing B Degroote Jeroen J Spranghers Thomas T Van Noten Noémie N Majdeddin Maryam M Van Poucke Mario M Peelman Luc L De Vrieze Jo J Boon Nico N Gielen Ingrid I Smet Stefaan De S Chen Daiwen D Michiels Joris J
BMC veterinary research 20201016 1
<h4>Background</h4>Early-life antibiotic administration is known to affect gut microbiota and host adiposity, but the effects of antibiotic exposure on skeletal muscle properties remain unknown. The present study evaluated the changes in skeletal muscle properties including myofiber characteristics and composition, as well as intramuscular fat (IMF) content in skeletal muscle of piglets when exposed to a tylosin-containing diet.<h4>Results</h4>A total of 18 piglets (28 days of age) were randomly ...[more]
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