Ontology highlight
ABSTRACT:
SUBMITTER: Guo L
PROVIDER: S-EPMC7570242 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Guo Lilong L Glover Janiece J Risner Alyssa A Wang Christina C Fulmer Diana D Moore Kelsey K Gensemer Cortney C Rumph Mary Kate MK Moore Reece R Beck Tyler T Norris Russell A RA
Journal of cardiovascular development and disease 20200817 3
β-catenin has been widely studied in many animal and organ systems across evolution, and gain or loss of function has been linked to a number of human diseases. Yet fundamental knowledge regarding its protein expression and localization remains poorly described. Thus, we sought to define whether there was a temporal and cell-specific regulation of β-catenin activities that correlate with distinct cardiac morphological events. Our findings indicate that activated nuclear β-catenin is primarily ev ...[more]