Ontology highlight
ABSTRACT:
SUBMITTER: Kalimuthu S
PROVIDER: S-EPMC7570320 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Microorganisms 20200820 9
An imbalance of homeostasis between the microbial communities and the host system leads to dysbiosis in oral micro flora. DMTU (1,3-di-m-tolyl-urea) is a biocompatible compound that was shown to inhibit <i>Streptococcus mutans</i> biofilm by inhibiting its communication system (quorum sensing). Here, we hypothesized that DMTU is able to inhibit multispecies biofilms. We developed a multispecies oral biofilm model, comprising an early colonizer <i>Streptococcus gordonii</i>, a bridge colonizer <i ...[more]