Ontology highlight
ABSTRACT:
SUBMITTER: Zhang X
PROVIDER: S-EPMC7571188 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Zhang Xinjun X Meng Yuhuan Y Houghton Paul P Liu Mingyu M Kanthaswamy Sreetharan S Oldt Robert R Ng Jillian J Trask Jessica Satkoski JS Huang Ren R Singh Balbir B Du Hongli H Smith David Glenn DG
Journal of medical primatology 20170307 2
<h4>Background</h4>Most cynomolgus macaques (Macaca fascicularis) used in the United States as animal models are imported from Chinese breeding farms without documented ancestry. Cynomolgus macaques with varying rhesus macaque ancestry proportions may exhibit differences, such as susceptibility to malaria, that affect their suitability as a research model.<h4>Methods</h4>DNA of 400 cynomolgus macaques from 10 Chinese breeding farms was genotyped to characterize their regional origin and rhesus a ...[more]