Effects of dexmedetomidine as a perineural adjuvant for femoral nerve block: A systematic review and meta-analysis.

ABSTRACT:

Background

Femoral nerve block (FNB) is one of the first-line analgesic methods for patients following lower extremity surgery. However, FNB with local anesthetics alone exert limited potency and supplemental opioids are often required. Dexmedetomidine (DEX) has been used to improve the analgesic effects of FNB. The present systematic review and meta-analysis were conducted to evaluate the effectiveness of DEX as an adjuvant to local anesthetics for FNB.

Methods

Randomized controlled trials comparing the effects of DEX versus sham control in combination with local anesthetics for FNB were included in this meta-analysis. Postoperative pain scores, duration of analgesic effects, and postoperative narcotic consumption were outcomes of interest. This research was performed accor

SUBMITTER: Zhao ZF 

PROVIDER: S-EPMC7571703 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature