Dstac Regulates Excitation-Contraction Coupling in Drosophila Body Wall Muscles.
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ABSTRACT:
SUBMITTER: Hsu IU
PROVIDER: S-EPMC7573238 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Dstac Regulates Excitation-Contraction Coupling in <i>Drosophila</i> Body Wall Muscles.
Hsu I-Uen IU Linsley Jeremy W JW Reid Lilly E LE Hume Richard I RI Leflein Ari A Kuwada John Y JY
Frontiers in physiology 20201006
Stac3 regulates excitation-contraction coupling (EC coupling) in vertebrate skeletal muscles by regulating the L-type voltage-gated calcium channel (Ca<sub>v</sub> channel). Recently a <i>stac</i>-like gene, <i>Dstac</i>, was identified in <i>Drosophila</i> and found to be expressed by both a subset of neurons and muscles. Here, we show that Dstac and Dmca1D, the <i>Drosophila</i> L-type Ca<sub>v</sub> channel, are necessary for normal locomotion by larvae. Immunolabeling with specific antibodie ...[more]
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