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Serious neonatal morbidities are associated with differences in DNA methylation among very preterm infants.

ABSTRACT: BACKGROUND:Infants born very preterm are more likely to experience neonatal morbidities compared to their term peers. Variations in DNA methylation (DNAm) associated with these morbidities may yield novel information about the processes impacted by these morbidities. METHODS:This study included 532 infants born?

SUBMITTER: Everson TM 

PROVIDER: S-EPMC7574188 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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<h4>Background</h4>Infants born very preterm are more likely to experience neonatal morbidities compared to their term peers. Variations in DNA methylation (DNAm) associated with these morbidities may yield novel information about the processes impacted by these morbidities.<h4>Methods</h4>This study included 532 infants born < 30 weeks gestation, participating in the Neonatal Neurobehavior and Outcomes in Very Preterm Infants study. We used a neonatal morbidity risk score, which was an additive  ...[more]

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