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Magnetic resonance imaging compared to ultrasonography in giant cell arteritis: a cross-sectional study.


ABSTRACT: BACKGROUND:There has been a shift in recent years to using ultrasound (US) and magnetic resonance imaging (MRI) as first-line investigations for suspected cranial large vessel vasculitis (LVV) and is a new recommendation by the EULAR 2018 guidelines for imaging in LVV. This cross-sectional study compares the performance of US and MRI and contrast-enhanced magnetic resonance angiography (MRA) for detecting vasculitis in patients with giant cell arteritis (GCA). METHODS:Patients with new-onset or already diagnosed GCA were recruited. The common temporal arteries and supra-aortic large vessels were evaluated by US and MRI/MRA. Blinded experts read the images and applied a dichotomous score (vasculitis: yes/no) in each vessel. RESULTS:Thirty-seven patients with giant cell arteritis (GCA) were recruited. Two patients were excluded. Of the remaining patients, nine had new-onset disease and 26 had established disease. Mean age was 71?years, and median C-reactive protein (CRP) was 7.5?mg/L. The median time between US and MRI was 1?day. Overall, US revealed vasculitic changes more frequently than MRI (p?

SUBMITTER: Yip A 

PROVIDER: S-EPMC7574248 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Magnetic resonance imaging compared to ultrasonography in giant cell arteritis: a cross-sectional study.

Yip Ashley A   Jernberg Elizabeth Torrey ET   Bardi Mohammad M   Geiger Julia J   Lohne Frode F   Schmidt Wolfgang Andreas WA   Myklebust Geirmund G   Diamantopoulos Andreas P AP  

Arthritis research & therapy 20201019 1


<h4>Background</h4>There has been a shift in recent years to using ultrasound (US) and magnetic resonance imaging (MRI) as first-line investigations for suspected cranial large vessel vasculitis (LVV) and is a new recommendation by the EULAR 2018 guidelines for imaging in LVV. This cross-sectional study compares the performance of US and MRI and contrast-enhanced magnetic resonance angiography (MRA) for detecting vasculitis in patients with giant cell arteritis (GCA).<h4>Methods</h4>Patients wit  ...[more]

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