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OposSOM-Browser: an interactive tool to explore omics data landscapes in health science.

ABSTRACT: BACKGROUND:oposSOM is a comprehensive, machine learning based open-source data analysis software combining functionalities such as diversity analyses, biomarker selection, function mining, and visualization. RESULTS:These functionalities are now available as interactive web-browser application for a broader user audience interested in extracting detailed information from high-throughput omics data sets pre-processed by oposSOM. It enables interactive browsing of single-gene and gene set profiles, of molecular 'portrait landscapes', of associated phenotype diversity, and signalling pathway activation patterns. CONCLUSION:The oposSOM-Browser makes available interactive data browsing for five transcriptome data sets of cancer (melanomas, B-cell lymphomas, gliomas) and of peripheral blood (sepsis and healthy individuals) at www.izbi.uni-leipzig.de/opossom-browser .

SUBMITTER: Loeffler-Wirth H

PROVIDER: S-EPMC7574456 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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oposSOM-Browser: an interactive tool to explore omics data landscapes in health science.

Loeffler-Wirth Henry H Reikowski Jasmin J Hakobyan Siras S Wagner Jonas J Binder Hans H

BMC bioinformatics 20201019 1

<h4>Background</h4>oposSOM is a comprehensive, machine learning based open-source data analysis software combining functionalities such as diversity analyses, biomarker selection, function mining, and visualization.<h4>Results</h4>These functionalities are now available as interactive web-browser application for a broader user audience interested in extracting detailed information from high-throughput omics data sets pre-processed by oposSOM. It enables interactive browsing of single-gene and ge ...[more]

PMID: 33076824

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