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Association between serum CCL-18 and IL-23 concentrations and disease progression of chronic obstructive pulmonary disease.


ABSTRACT: This study aimed to investigate the association between serum concentrations of chemokine (C-C Motif) ligand 18 (CCL-18) and interleukin 23 (IL-23) and clinical parameters of chronic obstructive pulmonary disease (COPD). The serum concentrations of CCL-18 and IL-23 were tested by enzyme linked immunosorbent assay (ELISA). The association between their concentrations and clinical parameters of COPD patients were analyzed by linear regression, logistic regression and ROC curve. The results showed that the serum concentrations of CCL-18 and IL-23 in COPD patients were increased compared with healthy people (P?

SUBMITTER: Rong B 

PROVIDER: S-EPMC7576212 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Association between serum CCL-18 and IL-23 concentrations and disease progression of chronic obstructive pulmonary disease.

Rong Biaoxue B   Fu Tian T   Rong Congxue C   Liu Wen W   Li Kai K   Liu Hua H  

Scientific reports 20201020 1


This study aimed to investigate the association between serum concentrations of chemokine (C-C Motif) ligand 18 (CCL-18) and interleukin 23 (IL-23) and clinical parameters of chronic obstructive pulmonary disease (COPD). The serum concentrations of CCL-18 and IL-23 were tested by enzyme linked immunosorbent assay (ELISA). The association between their concentrations and clinical parameters of COPD patients were analyzed by linear regression, logistic regression and ROC curve. The results showed  ...[more]

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