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Unlocking the efficiency of genomics laboratories with robotic liquid-handling.

ABSTRACT: In research and clinical genomics laboratories today, sample preparation is the bottleneck of experiments, particularly when it comes to high-throughput next generation sequencing (NGS). More genomics laboratories are now considering liquid-handling automation to make the sequencing workflow more efficient and cost effective. The question remains as to its suitability and return on investment. A number of points need to be carefully considered before introducing robots into biological laboratories. Here, we describe the state-of-the-art technology of both sophisticated and do-it-yourself (DIY) robotic liquid-handlers and provide a practical review of the motivation, implications and requirements of laboratory automation for genome sequencing experiments.

SUBMITTER: Tegally H

PROVIDER: S-EPMC7576741 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Unlocking the efficiency of genomics laboratories with robotic liquid-handling.

Tegally Houriiyah H San James Emmanuel JE Giandhari Jennifer J de Oliveira Tulio T

BMC genomics 20201020 1

In research and clinical genomics laboratories today, sample preparation is the bottleneck of experiments, particularly when it comes to high-throughput next generation sequencing (NGS). More genomics laboratories are now considering liquid-handling automation to make the sequencing workflow more efficient and cost effective. The question remains as to its suitability and return on investment. A number of points need to be carefully considered before introducing robots into biological laboratori ...[more]

PMID: 33081689

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