Serum symmetric dimethylarginine concentration in healthy horses and horses with acute kidney injury.

ABSTRACT: BACKGROUND:There are limited options to diagnose acute kidney injury (AKI) in horses. Symmetric dimethylarginine (SDMA) is routinely used in human and small animal medicine. The aim of this study was to assess serum SDMA concentrations in healthy horses and horses with AKI. The objective of this study was to evaluate the association of: 1) age, 2) sex, 3) body weight and 4) serum creatinine and urea levels on serum SDMA concentrations. Fifty-three healthy horses, including 17 foals (2-6?months of age) and 36 adult horses (3-29?years of age), and 23 horses with AKI were included in the study based on history, physical examination, blood analysis, urinalysis and an ultrasonographic examination of the urinary tract. Serum SDMA concentrations were measured using a non-species specific commercial ELISA test. RESULTS:In healthy adult horses, the value of SDMA was 0.53?±?0.14??mol/L. The value was higher in foals (1.5?±?0.4??mol/L, P?

SUBMITTER: Siwinska N 

PROVIDER: S-EPMC7576750 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature