Ontology highlight
ABSTRACT:
SUBMITTER: Vafaei S
PROVIDER: S-EPMC7576823 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Vafaei Somayeh S Saeednejad Zanjani Leili L Habibi Shams Zohreh Z Naseri Marzieh M Fattahi Fahimeh F Gheytanchi Elmira E Alemrajabi Mahdi M Ebrahimi Marzieh M Madjd Zahra Z
Scientific reports 20201020 1
To explore the proper prognostic markers for the likelihood of metastasis in CRC patients. Seventy-seven fresh CRC samples were collected to evaluate the mRNA level of the selected marker using Real-time PCR. Moreover, 648 formalin-fixed paraffin-embedded CRC tissues were gathered to evaluate protein expression by immunohistochemistry (IHC) on tissue microarrays. The results of Real-Time PCR showed that low expression of Talin1 was significantly associated with advanced TNM stage (p = 0.034) as ...[more]