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Antibiotic Consumption and Stewardship at a Hospital outside of an Early Coronavirus Disease 2019 Epicenter.


ABSTRACT: There are scant data on the impact of coronavirus disease 2019 (COVID-19) on hospital antibiotic consumption, and no data from outside epicenters. At our nonepicenter hospital, antibiotic days of therapy (DOT) and bed days of care (BDOC) were reduced by 151.5/month and 285/month, respectively, for March to June 2020 compared to 2018-2019 (P?=?0.001 and P?0.001). DOT per 1,000 BDOC was increased (8.1/month; P?=?0.001). COVID-19 will impact antibiotic consumption, stewardship, and resistance in ways that will likely differ temporally and by region.

SUBMITTER: Buehrle DJ 

PROVIDER: S-EPMC7577150 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Antibiotic Consumption and Stewardship at a Hospital outside of an Early Coronavirus Disease 2019 Epicenter.

Buehrle Deanna J DJ   Decker Brooke K BK   Wagener Marilyn M MM   Adalja Amesh A   Singh Nina N   McEllistrem Mary C MC   Nguyen M Hong MH   Clancy Cornelius J CJ  

Antimicrobial agents and chemotherapy 20201020 11


There are scant data on the impact of coronavirus disease 2019 (COVID-19) on hospital antibiotic consumption, and no data from outside epicenters. At our nonepicenter hospital, antibiotic days of therapy (DOT) and bed days of care (BDOC) were reduced by 151.5/month and 285/month, respectively, for March to June 2020 compared to 2018-2019 (<i>P = </i>0.001 and <i>P < </i>0.001). DOT per 1,000 BDOC was increased (8.1/month; <i>P = </i>0.001). COVID-19 will impact antibiotic consumption, stewardshi  ...[more]

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