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Incidence, determinants and consequences of delirium in older patients after transcatheter aortic valve implantation.


ABSTRACT: BACKGROUND:delirium is an event leading to negative health outcomes and increased mortality in patients. The aim of this study is to investigate the incidence, determinants and consequences of post-operative delirium (POD) in older patients undergoing transcatheter aortic valve implantation (TAVI). METHODS:The TAVI Care and Cure program is a prospective, observational registry in patients referred for TAVI at Erasmus University Medical Centre. The presence of delirium was evaluated by daily clinical assessment by a geriatrician pre- and up to 3 days post-TAVI. Mortality data were obtained from the Dutch Civil Registry. RESULTS:A total of 543 patients underwent TAVI between January 2014 and December 2017. Overall, the incidence of POD was 14% (75/543 patients) but declined from 18% in 2014 to 7% in 2017 (P =?0.009). Patients who developed POD were older (81.9?±?5.8 versus 78.6?±?8.3 years, P 

SUBMITTER: Goudzwaard JA 

PROVIDER: S-EPMC7577406 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Incidence, determinants and consequences of delirium in older patients after transcatheter aortic valve implantation.

Goudzwaard Jeannette A JA   de Ronde-Tillmans Marjo J A G MJAG   de Jager Tom A J TAJ   Lenzen Mattie J MJ   Nuis Rutger-Jan RJ   van Mieghem Nicolas M NM   Daemen Joost J   de Jaegere Peter P T PPT   Mattace-Raso Francesco U S FUS  

Age and ageing 20200401 3


<h4>Background</h4>delirium is an event leading to negative health outcomes and increased mortality in patients. The aim of this study is to investigate the incidence, determinants and consequences of post-operative delirium (POD) in older patients undergoing transcatheter aortic valve implantation (TAVI).<h4>Methods</h4>The TAVI Care and Cure program is a prospective, observational registry in patients referred for TAVI at Erasmus University Medical Centre. The presence of delirium was evaluate  ...[more]

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