Ontology highlight
ABSTRACT:
SUBMITTER: Reim D
PROVIDER: S-EPMC7578278 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Reim Daniel D Novotny Alexander A Friess Helmut H Slotta-Huspenina Julia J Weichert Wilko W Ott Katja K Dislich Bastian B Lorenzen Sylvie S Becker Karen K Langer Rupert R
The journal of pathology. Clinical research 20200513 4
The presence of lymph node (LN) metastases is one of the most important negative prognostic factors in upper gastrointestinal carcinomas. Tumour regression similar to that in primary tumours can be observed in LN metastases after neoadjuvant therapy. We evaluated the prognostic impact of histological regression in LNs in 480 adenocarcinomas of the stomach and gastro-oesophageal junction after neoadjuvant chemotherapy. Regressive changes in LNs (nodular and/or hyaline fibrosis, sheets of foamy hi ...[more]