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Diaphragmatic myoclonus due to SARS-CoV-2 infection.

ABSTRACT: A wide range of neurological signs and symptoms have been associated with SARS-CoV-2 infection. In the present report, we described two Italian patients diagnosed with diaphragmatic myoclonus after COVID-19. In both cases, mild lymphocytosis at cerebrospinal fluid analysis and no structural brain changes were reported. The pathophysiological origin of the myoclonus in the two cases was different. In case 1, electroencephalogram did not reveal any cortical correlates and brain imaging of the spine was unremarkable, while in case 2, cortical origin of myoclonus was demonstrated. With the present two cases, we confirm and extend the neurological manifestations of SARS-CoV-2 infection.

SUBMITTER: Borroni B

PROVIDER: S-EPMC7579554 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Diaphragmatic myoclonus due to SARS-CoV-2 infection.

Borroni Barbara B Gazzina Stefano S Dono Fedele F Mazzoleni Valentina V Liberini Paolo P Carrarini Claudia C Russo Mirella M Pontolillo Michela M Vecchiet Jacopo J Onofrj M M Bonanni Laura L

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20201022 12

A wide range of neurological signs and symptoms have been associated with SARS-CoV-2 infection. In the present report, we described two Italian patients diagnosed with diaphragmatic myoclonus after COVID-19. In both cases, mild lymphocytosis at cerebrospinal fluid analysis and no structural brain changes were reported. The pathophysiological origin of the myoclonus in the two cases was different. In case 1, electroencephalogram did not reveal any cortical correlates and brain imaging of the spin ...[more]

PMID: 33090303

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