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Zinc and COVID-19: Basis of Current Clinical Trials.

ABSTRACT: Coronavirus disease-2019 (COVID-19) pandemic continues to threaten patients, societies, and economic and healthcare systems around the world. Like many other diseases, the host immune system determines the progress of COVID-19 and fatality. Modulation of inflammatory response and cytokine production using immunonutrition is a novel concept that has been applied to other diseases as well. Zinc, one of the anti-inflammatory and antioxidant micronutrient found in food with well-established role in immunity, is currently being used in some clinical trials against COVID-19. This review integrates the contemporary studies of role of zinc in antiviral immunity along with discussing its potential role against COVID-19, and ongoing COVID-19 clinical trials using zinc.

SUBMITTER: Pal A

PROVIDER: S-EPMC7580816 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Zinc and COVID-19: Basis of Current Clinical Trials.

Pal Amit A Squitti Rosanna R Picozza Mario M Pawar Anil A Rongioletti Mauro M Dutta Atanu Kumar AK Sahoo Sibasish S Goswami Kalyan K Sharma Praveen P Prasad Rajendra R

Biological trace element research 20201022 8

Coronavirus disease-2019 (COVID-19) pandemic continues to threaten patients, societies, and economic and healthcare systems around the world. Like many other diseases, the host immune system determines the progress of COVID-19 and fatality. Modulation of inflammatory response and cytokine production using immunonutrition is a novel concept that has been applied to other diseases as well. Zinc, one of the anti-inflammatory and antioxidant micronutrient found in food with well-established role in ...[more]

PMID: 33094446

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