The prognostic role of tissue TLR2 and TLR4 in colorectal cancer.
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ABSTRACT:
SUBMITTER: Beilmann-Lehtonen I
PROVIDER: S-EPMC7581516 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Publications
The prognostic role of tissue TLR2 and TLR4 in colorectal cancer.
Beilmann-Lehtonen Ines I Böckelman Camilla C Mustonen Harri H Koskensalo Selja S Hagström Jaana J Haglund Caj C
Virchows Archiv : an international journal of pathology 20200519 5
Colorectal cancer (CRC), the second most common cancer globally, resulted in 881,000 deaths in 2018. Toll-like receptors (TLRs) are crucial to detecting pathogen invasion and inducing the host's immune response. This study aimed to explore the prognostic value of TLR2 and TLR4 tumor expressions in colorectal cancer patients. We studied the immunohistochemical expressions of TLR2 and TLR4 using tissue microarray specimens from 825 patients undergoing surgery in the Department of Surgery, Helsinki ...[more]
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