Ontology highlight
ABSTRACT:
SUBMITTER: de Vries JJ
PROVIDER: S-EPMC7582521 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
de Vries Judith J JJ Hoppenbrouwers Tamara T Martinez-Torres Cristina C Majied Rezin R Özcan Behiye B van Hoek Mandy M Leebeek Frank W G FWG Rijken Dingeman C DC Koenderink Gijsje H GH de Maat Moniek P M MPM
International journal of molecular sciences 20200926 19
Subjects with diabetes mellitus (DM) have an increased risk of arterial thrombosis, to which changes in clot structure and mechanics may contribute. Another contributing factor might be an increased formation of neutrophil extracellular traps (NETs) in DM. NETs are mainly formed during the acute phase of disease and form a network within the fibrin matrix, thereby influencing clot properties. Previous research has shown separate effects of NETs and DM on clot properties, therefore our aim was to ...[more]