Dual decline in gait speed and cognition is associated with future dementia: evidence for a phenotype.

ABSTRACT:

Background

concurrent declines in gait speed and cognition have been associated with future dementia. However, the clinical profile of 'dual decliners', those with concomitant decline in both gait speed and cognition, has not been yet described. We aimed to describe the phenotype and the risk for incident dementia of those who present with dual decline in comparison with non-dual decliners.

Methods

prospective cohort of community-dwelling older adults free of dementia at baseline. We evaluated participants' gait speed, cognition, medical status, functionality, incidence of adverse events and dementia, biannually over 7 years. Gait speed was assessed with a 6-m electronic walkway and global cognition using the MoCA test. We compared characteristics between dual decliners and

SUBMITTER: Montero-Odasso M 

PROVIDER: S-EPMC7583522 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature