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The Impact of Compulsivity and Impulsivity in Cerebellar Ataxia: A Case Series.

ABSTRACT: Background:The cerebellum has recently been identified to have a key role in reward processing, and individuals with ataxia have been found to be more impulsive and compulsive as part of cerebellum-related cognitive and behavioral disturbances. Case Report:We reported five individuals with cerebellar ataxia who demonstrate impulsive and compulsive behaviors, including hobbyism, gambling, and compulsive medication use, to illustrate that these symptoms can be highly disabling. Discussion:These five cases provide examples of behavioral symptoms in cerebellar ataxia. Further investigations of the pathomechanism of these symptoms will advance our understanding of the cerebellum in cognition and behavior.

SUBMITTER: Amokrane N

PROVIDER: S-EPMC7583703 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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The Impact of Compulsivity and Impulsivity in Cerebellar Ataxia: A Case Series.

Amokrane Nadia N Lin Chi-Ying R CR Desai Natasha A NA Kuo Sheng-Han SH

Tremor and other hyperkinetic movements (New York, N.Y.) 20201016

<h4>Background</h4>The cerebellum has recently been identified to have a key role in reward processing, and individuals with ataxia have been found to be more impulsive and compulsive as part of cerebellum-related cognitive and behavioral disturbances.<h4>Case report</h4>We reported five individuals with cerebellar ataxia who demonstrate impulsive and compulsive behaviors, including hobbyism, gambling, and compulsive medication use, to illustrate that these symptoms can be highly disabling.<h4>D ...[more]

PMID: 33133767

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