Ontology highlight
ABSTRACT:
SUBMITTER: Troncoso F
PROVIDER: S-EPMC7583763 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Troncoso Felipe F Herlitz Kurt K Acurio Jesenia J Aguayo Claudio C Guevara Katherine K Castro Fidel Ovidio FO Godoy Alejandro S AS San Martin Sebastian S Escudero Carlos C
International journal of molecular sciences 20200928 19
Estrogenic steroids and adenosine A<sub>2A</sub> receptors promote the wound healing and angiogenesis processes. However, so far, it is unclear whether estrogen may regulate the expression and pro-angiogenic activity of A<sub>2A</sub> receptors. Using in vivo analyses, we showed that female wild type (WT) mice have a more rapid wound healing process than female or male A<sub>2A</sub>-deficient mice (A<sub>2A</sub>KO) mice. We also found that pulmonary endothelial cells (mPEC) isolated from femal ...[more]