Ontology highlight
ABSTRACT:
SUBMITTER: Kiouptsi K
PROVIDER: S-EPMC7583822 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Kiouptsi Klytaimnistra K Jäckel Sven S Wilms Eivor E Pontarollo Giulia G Winterstein Jana J Karwot Cornelia C Groß Kathrin K Jurk Kerstin K Reinhardt Christoph C
International journal of molecular sciences 20200928 19
The commensal microbiota is a recognized enhancer of arterial thrombus growth. While several studies have demonstrated the prothrombotic role of the gut microbiota, the molecular mechanisms promoting arterial thrombus growth are still under debate. Here, we demonstrate that germ-free (GF) mice, which from birth lack colonization with a gut microbiota, show diminished static deposition of washed platelets to type I collagen compared with their conventionally raised (CONV-R) counterparts. Flow cyt ...[more]