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Allylic Amination of Alkenes with Iminothianthrenes to Afford Alkyl Allylamines.

ABSTRACT: Allylic C-H amination is currently accomplished with (sulfon)amides or carbamates. Here we show the first allylic amination that can directly afford alkyl allylamines, enabled by the reactivity of thianthrene-based nitrogen sources that can be prepared from primary amines in a single step.

SUBMITTER: Cheng Q

PROVIDER: S-EPMC7584367 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Allylic Amination of Alkenes with Iminothianthrenes to Afford Alkyl Allylamines.

Cheng Qiang Q Chen Junting J Lin Songyun S Ritter Tobias T

Journal of the American Chemical Society 20201001 41

Allylic C-H amination is currently accomplished with (sulfon)amides or carbamates. Here we show the first allylic amination that can directly afford alkyl allylamines, enabled by the reactivity of thianthrene-based nitrogen sources that can be prepared from primary amines in a single step. ...[more]

PMID: 33001638

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