Ontology highlight
ABSTRACT:
SUBMITTER: Al-Eitan LN
PROVIDER: S-EPMC7584512 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Al-Eitan Laith N LN Al-Dalala Islam M IM Elshammari Afrah K AK Khreisat Wael H WH Nimiri Aseel F AF Alnaamneh Adan H AH Aljamal Hanan A HA Alghamdi Mansour A MA
Pharmacogenomics and personalized medicine 20201016
<h4>Purpose</h4>The aim of this study was to investigate the possible effects of single-nucleotide polymorphisms (SNPs) within SLC1A1, SLC6A1, FAM131B, GPLD1, F2, GABRG2, GABRA1, and CACNG5 genes on response to anti-epileptic drugs (AEDs) and the genetic predisposition of epilepsy in Jordanian patients.<h4>Patients and methods</h4>A total of 299 healthy individuals and 296 pediatric patients from the Jordanian population were recruited. Blood samples are collected, and genotyping was performed u ...[more]