Ontology highlight
ABSTRACT:
SUBMITTER: Jiang S
PROVIDER: S-EPMC7585871 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Jiang Sijia S Chen Qian Q Liu Haihua H Gao Yue Y Yang Xiaoxue X Ren Zhonglu Z Gao Yunfei Y Xiao Lu L Zhong Mei M Yu Yanhong Y Yang Xinping X
Molecular therapy. Nucleic acids 20201009
Preeclampsia is believed to be caused by impaired placentation with insufficient trophoblast invasion, leading to impaired uterine spiral artery remodeling and angiogenesis. However, the underlying molecular mechanism remains unknown. We recently carried out transcriptome profiling of placental long noncoding RNAs (lncRNAs) and identified 383 differentially expressed lncRNAs in early-onset severe preeclampsia. Here, we are reporting our identification of lncRNA <i>INHBA-AS1</i> as a potential ca ...[more]