Ontology highlight
ABSTRACT:
SUBMITTER: Ziman B
PROVIDER: S-EPMC7586133 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Ziman Benjamin B Barghouth Paul G PG Maciel Eli Isael EI Oviedo Néstor J NJ
iScience 20201009 11
Tissue homeostasis relies on the timely renewal of cells that have been damaged or have surpassed their biological age. Nonetheless, the underlying molecular mechanism coordinating tissue renewal is unknown. The planarian <i>Schmidtea mediterranea</i> harbors a large population of stem cells that continuously divide to support the restoration of tissues throughout the body. Here, we identify that TNF Receptor Associated Factors (TRAFs) play critical roles in cellular survival during tissue repai ...[more]