Ontology highlight
ABSTRACT:
SUBMITTER: Bunu G
PROVIDER: S-EPMC7589469 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Bunu Gabriela G Toren Dmitri D Ion Catalin-Florentin CF Barardo Diogo D Sârghie Larisa L Grigore Laurentiu Gabriel LG de Magalhães João Pedro JP Fraifeld Vadim E VE Tacutu Robi R
Scientific data 20201026 1
Interventional studies on genetic modulators of longevity have significantly changed gerontology. While available lifespan data are continually accumulating, further understanding of the aging process is still limited by the poor understanding of epistasis and of the non-linear interactions between multiple longevity-associated genes. Unfortunately, based on observations so far, there is no simple method to predict the cumulative impact of genes on lifespan. As a step towards applying predictive ...[more]