Ontology highlight
ABSTRACT:
SUBMITTER: Crauciuc GA
PROVIDER: S-EPMC7589771 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Crauciuc George Andrei GA Iancu Mihaela M Olah Peter P Tripon Florin F Anciuc Mădălina M Gozar Liliana L Togănel Rodica R Bănescu Claudia C
International journal of environmental research and public health 20201021 20
This study aimed to investigate possible associations of the susceptibility to congenital heart defects (CHDs) with <i>AXIN1</i> rs1805105, rs12921862 and rs370681 gene variants and haplotypes<b>,</b> and <i>AXIN2</i> rs2240308 gene variant. Significant associations were identified for <i>AXIN1</i> rs370681 and <i>AXIN2</i> rs2240308 variants. <i>AXIN1</i> rs370681 variant was significantly associated with decreased odds of CHDs (adjusted OR varying from 0.13 to 0.28 in codominant, dominant and ...[more]