Vitamin D₃ metabolite ratio as an indicator of vitamin D status and its association with diabetes complications.

ABSTRACT:

Background

Vitamin D deficiency is diagnosed by total serum 25-hydroxyvitamin D (25(OH)D) concentration and is associated with poor health and increased mortality; however, some populations have low 25(OH) D concentrations without manifestations of vitamin D deficiency. The Vitamin D Metabolite Ratio (VMR) has been suggested as a superior indicator of vitamin D status. Therefore, VMR was determined in a population with type 2 diabetes at high risk for vitamin D deficiency and correlated with diabetic complications.

Research design and methods

Four hundred sisty patients with type 2 diabetes (T2D) were recruited, all were vitamin D₃ supplement naive. Plasma concentration of 25-hydroxyvitamin D₃ (25(OH)D₃) and its metabolites 1,25-dihydroxyvita

SUBMITTER: Ahmed LHM 

PROVIDER: S-EPMC7590744 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature