Assessing the prognostic value of stemness-related genes in breast cancer patients.
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ABSTRACT:
SUBMITTER: Wang WJ
PROVIDER: S-EPMC7591576 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Publications
Assessing the prognostic value of stemness-related genes in breast cancer patients.
Wang Wen-Jie WJ Wang Han H Wang Meng-Sen MS Huang Yue-Qing YQ Ma Yu-Yuan YY Qi Jie J Shi Jian-Ping JP Li Wei W
Scientific reports 20201027 1
Breast cancer (BC) is currently one of the deadliest tumors worldwide. Cancer stem cells (CSCs) are a small group of tumor cells with self-renewal and differentiation abilities and high treatment resistance. One of the reasons for treatment failures is the inability to completely eliminate tumor stem cells. By using the edgeR package, we identified stemness-related differentially expressed genes in GSE69280. Via Lasso-penalized Cox regression analysis and univariate Cox regression analysis, surv ...[more]
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