Ontology highlight
ABSTRACT:
SUBMITTER: Igase M
PROVIDER: S-EPMC7591904 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Igase Masaya M Nemoto Yuki Y Itamoto Kazuhito K Tani Kenji K Nakaichi Munekazu M Sakurai Masashi M Sakai Yusuke Y Noguchi Shunsuke S Kato Masahiro M Tsukui Toshihiro T Mizuno Takuya T
Scientific reports 20201027 1
Inhibition of programmed death 1 (PD-1), expressed on activated T cells, can break through immune resistance and elicit durable responses in human melanoma as well as other types of cancers. Canine oral malignant melanoma is one of the most aggressive tumors bearing poor prognosis due to its high metastatic potency. However, there are few effective treatments for the advanced stages of melanoma in veterinary medicine. Only one previous study indicated the potential of the immune checkpoint inhib ...[more]