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Renal transplant patient survives a donor-derived abdominal invasive mucormycosis (Lichtheimia ramos a).

ABSTRACT: Mucormycosis is a life-threatening invasive fungal infection, most commonly described in severely immunocompromised patients. It is characterized by rapid invasive growth of the fungus and often with fatal outcome. We report a case of a renal transplant recipient diagnosed with a donor-derived invasive mucormycosis. In this patient, we used a step-wise approach of withdrawal of immunosuppressants, antifungal induction therapy, extensive surgical debridement of all (potentially) infected tissue, abdominal irrigation of liposomal amphotericin B and interferon gamma. Due to rapid diagnosis and intensive therapy the patient survived.

SUBMITTER: Spithoven EM

PROVIDER: S-EPMC7593344 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Renal transplant patient survives a donor-derived abdominal invasive mucormycosis (<i>Lichtheimia ramos</i> <i>a</i>).

Spithoven E M EM Bruns A H W AHW Petri B J BJ Haas P J PJ Nguyen T Q TQ Hagen F F van Zuilen A D AD

Medical mycology case reports 20201023

Mucormycosis is a life-threatening invasive fungal infection, most commonly described in severely immunocompromised patients. It is characterized by rapid invasive growth of the fungus and often with fatal outcome. We report a case of a renal transplant recipient diagnosed with a donor-derived invasive mucormycosis. In this patient, we used a step-wise approach of withdrawal of immunosuppressants, antifungal induction therapy, extensive surgical debridement of all (potentially) infected tissue, ...[more]

PMID: 33145152

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