Effect of ambient air pollution on the incidence of colorectal cancer among a diabetic population: a nationwide nested case-control study in Taiwan.

ABSTRACT:

Objectives

An increasing number of studies had shown that air pollution exposure may aggravate blood glucose control in patients with diabetes, an independent risk factor for colorectal cancer (CRC) proposed by some researchers. This study aimed to investigate the impact of exposure to ambient particulate matter with aerodynamic diameters ≤2.5 μm (PM_2.5) on the incidence of CRC among a diabetic population.

Design

A nested case-control study.

Setting

A subset data retrieved from the Taiwan's National Health Insurance Research Database.

Participants

We identified patients with newly diagnosed diabetes (n=1 164 962) during 1999-2013. Participants who had subsequently developed an incident of CRC were placed into the case group, while controls were match

SUBMITTER: Ma JW 

PROVIDER: S-EPMC7594369 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature