Ontology highlight
ABSTRACT:
SUBMITTER: Hong H
PROVIDER: S-EPMC7594545 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Hong H H Dowdy D W DW Dooley K E KE Francis H W HW Budhathoki C C Han H-R HR Farley J E JE
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20200101 1
<b>SETTING:</b> The ototoxic effects of aminoglycosides (AGs) lead to permanent hearing loss, which is one of the devastating consequences of multidrug-resistant tuberculosis (MDR-TB) treatment. As AG ototoxicity is dose-dependent, the impact of a surrogate measure of AG exposure on AG-induced hearing loss warrants close attention for settings with limited therapeutic drug monitoring.<b>OBJECTIVE:</b> To explore the prognostic impact of cumulative AG dose on AG ototoxicity in patients following ...[more]