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Fecal Microbiota Transplants Annually and Their Positive Clinical Impact.


ABSTRACT:

Introduction

Although fecal microbiota transplantation (FMT) is a recommended, clinically efficacious, and cost-effective treatment for recurrent Clostridioides difficile infection (CDI), the scale of FMT use in the United States is unknown.

Methods

We developed a population-level CDI model.

Results

We estimated that 48,000 FMTs could be performed annually, preventing 32,000 CDI recurrences.

Discussion

Improving access to FMT could lead to tens of thousands fewer C. difficile episodes per year.

SUBMITTER: Mamoon L 

PROVIDER: S-EPMC7594930 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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Fecal Microbiota Transplants Annually and Their Positive Clinical Impact.

Mamoon Lamia L   Olesen Scott W SW  

Clinical and translational gastroenterology 20201101 11


<h4>Introduction</h4>Although fecal microbiota transplantation (FMT) is a recommended, clinically efficacious, and cost-effective treatment for recurrent Clostridioides difficile infection (CDI), the scale of FMT use in the United States is unknown.<h4>Methods</h4>We developed a population-level CDI model.<h4>Results</h4>We estimated that 48,000 FMTs could be performed annually, preventing 32,000 CDI recurrences.<h4>Discussion</h4>Improving access to FMT could lead to tens of thousands fewer C.  ...[more]

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