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A Retrospective Cohort Study to Investigate the Incidence of Cachexia During Chemotherapy in Patients with Colorectal Cancer.


ABSTRACT: INTRODUCTION:This retrospective study focused on cancer cachexia in clinical practice. We evaluated the incidence of cancer cachexia and the relationship between cancer cachexia and overall survival (OS) or toxicities in patients with advanced colorectal cancer after undergoing first-line systemic chemotherapy. METHODS:We examined 150 patients with colorectal cancer who underwent first-line systemic chemotherapy between February 1, 2010 and August 31, 2016 at Shizuoka Cancer Center Hospital and Kurume University Hospital. Cancer cachexia was defined as?>?5% weight loss or?>?2% weight loss with a body mass index of

SUBMITTER: Shibata M 

PROVIDER: S-EPMC7595989 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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A Retrospective Cohort Study to Investigate the Incidence of Cachexia During Chemotherapy in Patients with Colorectal Cancer.

Shibata Masayuki M   Fukahori Masaru M   Kasamatsu Eiji E   Machii Koji K   Hamauchi Satoshi S  

Advances in therapy 20201016 12


<h4>Introduction</h4>This retrospective study focused on cancer cachexia in clinical practice. We evaluated the incidence of cancer cachexia and the relationship between cancer cachexia and overall survival (OS) or toxicities in patients with advanced colorectal cancer after undergoing first-line systemic chemotherapy.<h4>Methods</h4>We examined 150 patients with colorectal cancer who underwent first-line systemic chemotherapy between February 1, 2010 and August 31, 2016 at Shizuoka Cancer Cente  ...[more]

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