Ontology highlight
ABSTRACT:
SUBMITTER: Quintero Escobar M
PROVIDER: S-EPMC7596414 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Quintero Escobar Melissa M Costa Tássia Brena Barroso Carneiro TBBC Martins Lucas G LG Costa Silvia S SS vanHelvoort Lengert André A Boldrini Érica É Morini da Silva Sandra Regina SR Lopes Luiz Fernando LF Vidal Daniel Onofre DO Krepischi Ana C V ACV Maschietto Mariana M Tasic Ljubica L
Frontiers in oncology 20201016
Pediatric osteosarcoma outcomes have improved over the last decades; however, patients who do not achieve a full resection of the tumor, even after aggressive chemotherapy, have the worst prognosis. At a genetic level, osteosarcoma presents many alterations, but there is scarce information on alterations at metabolomic levels. Therefore, an untargeted nuclear magnetic resonance metabonomic approach was used to reveal blood serum alterations, when samples were taken from 21 patients with osteosar ...[more]