Ontology highlight
ABSTRACT:
SUBMITTER: van Rooij BJM
PROVIDER: S-EPMC7596481 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
van Rooij Britt J M BJM Závodszky Gábor G Hoekstra Alfons G AG Ku David N DN
Scientific reports 20201029 1
Occlusive thrombi formed under high flow shear rates develop very rapidly in arteries and may lead to myocardial infarction or stroke. Rapid platelet accumulation (RPA) and occlusion of platelet-rich thrombi and clot shrinkage have been studied after flow arrest. However, the influence of margination and shear rate on occlusive clot formation is not fully understood yet. In this study, the influence of flow on the growth and shrinkage of a clot is investigated. Whole blood (WB) and platelet-rich ...[more]