Ontology highlight
ABSTRACT:
SUBMITTER: Landeros N
PROVIDER: S-EPMC7598708 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Landeros Natalia N Santoro Pablo M PM Carrasco-Avino Gonzalo G Corvalan Alejandro H AH
Cancers 20200924 10
The diffuse-type of gastric cancer (DGC), molecularly associated with epithelial to mesenchymal transition (EMT), is increasing in incidence. Loss of E-cadherin expression is the hallmark of the EMT process and is largely due to the upregulation of the EMT-inducing transcription factors ZEB1/2, Snail, Slug, and Twist1/2. However, ncRNA, such as miRNA and lncRNAs, can also participate in the EMT process through the direct targeting of E-cadherin and other EMT-inducing transcription factors. Addit ...[more]