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Towards reference values of pericoronary adipose tissue attenuation: impact of coronary artery and tube voltage in coronary computed tomography angiography.


ABSTRACT: OBJECTIVES:To determine normal pericoronary adipose tissue mean attenuation (PCATMA) values for left the anterior descending (LAD), left circumflex (LCX), and right coronary artery (RCA) in patients without plaques on coronary CT angiography (cCTA), taking into account tube voltage influence. METHODS:This retrospective study included 192 patients (76 (39.6%) men; median age 49 years (range, 19-79)) who underwent cCTA with third-generation dual-source CT for the suspicion of CAD between 2015 and 2017. We selected patients without plaque on cCTA. PCATMA was measured semi-automatically on cCTA images in the proximal segment of the three main coronary arteries with 10 mm length. Paired t-testing was used to compare PCATMA between combinations of two coronary arteries within each patient, and one-way ANOVA testing was used to compare PCATMA in different kV groups. RESULTS:The overall mean?±?standard deviation (SD) PCATMA was -?90.3?±?11.1 HU. PCATMA in men was higher than that in women: -?88.5?±?10.5 HU versus -?91.5?±?11.3 HU (p?=?0.001). PCATMA of LAD, LCX, and RCA was -?92.4?±?11.6 HU, -?88.4?±?9.9 HU, and -?90.2?±?11.4 HU, respectively. Pairwise comparison of the arteries showed significant difference in PCATMA: LAD and LCX (p?

SUBMITTER: Ma R 

PROVIDER: S-EPMC7599179 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Towards reference values of pericoronary adipose tissue attenuation: impact of coronary artery and tube voltage in coronary computed tomography angiography.

Ma Runlei R   Ties Daan D   van Assen Marly M   Pelgrim Gert Jan GJ   Sidorenkov Grigory G   van Ooijen Peter M A PMA   van der Harst Pim P   van Dijk Randy R   Vliegenthart Rozemarijn R  

European radiology 20200722 12


<h4>Objectives</h4>To determine normal pericoronary adipose tissue mean attenuation (PCAT<sub>MA</sub>) values for left the anterior descending (LAD), left circumflex (LCX), and right coronary artery (RCA) in patients without plaques on coronary CT angiography (cCTA), taking into account tube voltage influence.<h4>Methods</h4>This retrospective study included 192 patients (76 (39.6%) men; median age 49 years (range, 19-79)) who underwent cCTA with third-generation dual-source CT for the suspicio  ...[more]

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