Ontology highlight
ABSTRACT:
SUBMITTER: Watanabe T
PROVIDER: S-EPMC7599240 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Watanabe Takafumi T Nanamiya Hideaki H Kojima Manabu M Nomura Shinji S Furukawa Shigenori S Soeda Shu S Tanaka Daisuke D Isogai Takao T Imai Jun-Ichi JI Watanabe Shinya S Fujimori Keiya K
Scientific reports 20201030 1
It is well known that tumour initiation and progression are primarily an accumulation of genetic mutations. The mutation status of a tumour may predict prognosis and enable better selection of targeted therapies. In the current study, we analysed a total of 55 surgical tumours from stage IB-IIB cervical cancer (CC) patients who had undergone radical hysterectomy including pelvic lymphadenectomy, using a cancer panel covering 50 highly mutated tumorigenesis-related genes. In 35 patients (63.6%), ...[more]