Ontology highlight
ABSTRACT:
SUBMITTER: Yepes-Calderon M
PROVIDER: S-EPMC7600059 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Yepes-Calderón Manuela M Sotomayor Camilo G CG Rasmussen Daniel Guldager Kring DGK Hijmans Ryanne S RS Te Velde-Keyzer Charlotte A CA van Londen Marco M van Dijk Marja M Diepstra Arjan A Berger Stefan P SP Karsdal Morten Asser MA Bemelman Frederike J FJ de Fijter Johan W JW Kers Jesper J Florquin Sandrine S Genovese Federica F Bakker Stephan J L SJL Sanders Jan-Stephan JS Van Den Born Jacob J
Journal of clinical medicine 20201007 10
The PRO-C6 assay, a reflection of collagen type VI synthesis, has been proposed as a non-invasive early biomarker of kidney fibrosis. We aimed to investigate cross-sectional and longitudinal associations between plasma and urine PRO-C6 and proven histological changes after kidney transplantation. The current study is a post-hoc analysis of 94 participants of the MECANO trial, a 24-month prospective, multicenter, open-label, randomized, controlled trial aimed at comparing everolimus-based vs. cyc ...[more]