Ontology highlight
ABSTRACT:
SUBMITTER: Brunetti B
PROVIDER: S-EPMC7600251 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Brunetti Barbara B Muscatello Luisa V LV Letko Anna A Papa Valentina V Cenacchi Giovanna G Grillini Marco M Murgiano Leonardo L Jagannathan Vidhya V Drögemüller Cord C
Genes 20201008 10
A 9-month old male Jack Russell Terrier started showing paraparesis of the hindlimbs after a walk. Hospitalized, the dog went into cardiac arrest, and later died. Necroscopic examination revealed a severe thickness of the diaphragm, esophagus, and base of the tongue, leading to the diagnosis of muscular dystrophy. The histology confirmed the marked size variation, regeneration, and fibrosis replacement of the skeletal muscle fibers. Immunohistochemistry demonstrated the absence of dystrophin con ...[more]