Unknown

Dataset Information

0

Positive Anti-SSA/Ro Antibody in a Woman with SARS-CoV-2 Infection Using Immunophenotyping: A Case Report.


ABSTRACT: The clinical spectrum of novel coronavirus infection appears to be wide, encompassing asymptomatic infection, mild upper respiratory tract illness, and severe viral pneumonia, with respiratory failure and even death. Autoantibodies, especially antiphospholipid antibodies, can occur in severe infections. Other autoantibodies are seldom reported. Here, a 60-year-old female patient without dry-mouth symptoms detected positive for anti-60 kDa SSA/Ro antibodies on day 43 after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. To investigate this unique clinical case of SARS-CoV-2 infection, immunological characteristics of this case were detected by using flow cytometry and were compared to the other three groups of patients-health subjects, 2019 novel coronavirus disease (COVID-19) recovery patients, and Sjögren's syndrome (SS) patients. Monitoring the autoantibody level and the development of subsequently related autoimmune diseases are warranted after SARS-CoV-2 infection.

SUBMITTER: Huang PI 

PROVIDER: S-EPMC7600347 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

altmetric image

Publications

Positive Anti-SSA/Ro Antibody in a Woman with SARS-CoV-2 Infection Using Immunophenotyping: A Case Report.

Huang Po-I PI   Lin Ting-Chun TC   Liu Feng-Cheng FC   Ho Yi-Jung YJ   Lu Jeng-Wei JW   Lin Te-Yu TY  

Medicina (Kaunas, Lithuania) 20201005 10


The clinical spectrum of novel coronavirus infection appears to be wide, encompassing asymptomatic infection, mild upper respiratory tract illness, and severe viral pneumonia, with respiratory failure and even death. Autoantibodies, especially antiphospholipid antibodies, can occur in severe infections. Other autoantibodies are seldom reported. Here, a 60-year-old female patient without dry-mouth symptoms detected positive for anti-60 kDa SSA/Ro antibodies on day 43 after severe acute respirator  ...[more]

Similar Datasets

| S-EPMC7394202 | biostudies-literature
| S-EPMC8432056 | biostudies-literature
| S-SCDT-10_1038-S44318-024-00061-0 | biostudies-other
| S-EPMC3931307 | biostudies-literature
| S-EPMC8500413 | biostudies-literature
| S-EPMC3593727 | biostudies-literature
| S-EPMC8262823 | biostudies-literature
| S-EPMC8231659 | biostudies-literature
| S-EPMC7906708 | biostudies-literature
| S-EPMC5167557 | biostudies-literature